Field Safety Notice: Siemens - ADVIA®/Dimension® clinical Chemistry systems: N-Acetylcysteine (NAC) and Metamizole Interference with Trinder and Trinderlike reaction Assays

vrijdag 8 april 2016 16:00

Siemens Healthcare Diagnostics has become aware of N-Acetylcysteine (NAC) and Metamizole (Dipyrone) interference with Trinder and Trinder-like reaction assays. The Trinder reaction is a reaction where hydrogen peroxide is formed and subsequently reacts with a phenol derivative and aminoantipyrine in the presence of peroxidase to form a colored quinone product.